Clindamycin for Acne: Benefits and How to Use

When you're dealing with acne and you've exhausted all of the at-home treatments— like the glycolic acid serums, the salicylic acid toners, the mandelic acid peels, the soothing cica balms—and your acne is still not clearing up, it might be time to call in the big guns. And by big guns, we mean try the prescription route. Sometimes, your acne needs an intervention from a dermatologist, so today, we'd like to introduce you to a popular, prescription-only acne treatment called clindamycin. Learn more as experts Dr. Amir Karam and Dr. Marisa Garshick break down all the details about this acne-fighting prescription, below.

What Is Clindamycin?

Clindamycin, according to both Dr. Garshick and Dr. Karam, is an oral and topical antibiotic treatment that's designed to treat acne. "Clindamycin is an antibiotic," says Dr. Karam. "It's most commonly used in an oral form to treat various types of infections that can affect the body. It's also very specifically used for skin infections because of its coverage of the bacteria that cover and affect the skin. However, in the way of acne treatments, it's used as a topical treatment, not as an oral form."

Dr. Karam goes on to say that it's often used as a trial treatment because it's difficult to gauge how acne will respond to it. "Not every type of acne will respond to this. Sometimes acne can be hormonal, which means it won't respond well to clindamycin," he says. "Also, it's not clear why some people are responders and others are not, and why some people with the P. Acnes colonization on the skin never form acne while others do."

"While it can be used for all types of acne, it is most commonly prescribed in the setting of mild to moderate inflammatory acne and can be used in conjunction with oral medications in the setting of severe acne," Dr. Garshick adds. She explains that inflammatory acne often refers to breakouts that are red bumps and pustules.

Benefits of Clindamycin for Acne

• Reduces acne-causing bacteria: One of the biggest benefits of clindamycin for acne is that it decreases acne-causing bacteria. "As an antibiotic, it helps to reduce acne-causing bacteria and can be particularly helpful for inflammatory acne," explains Dr. Garshick.
• Pregnancy-safe option for acne: If you're pregnant, your options for safe, acne treatments are limited, since it's not safe to use treatments like retinol or salicylic acid. "[Clindamycin] is considered pregnancy-safe so it is a good option for those who are pregnant and looking to treat their acne," adds Dr. Garshick.
• Minimal side effects: According to Dr. Karam, clindamycin has minimal side effects topically. "Most of it would be related to the ingredients of alcohol, which can create some burning sensation to the skin and dryness."
• Decrease inflammation in pores: "[Clindamycin] can decrease the potential for infection and inflammation of the pores, which prevents acne from occurring," adds Dr. Karam.
  

Side Effects of Clindamycin

"As with any topical ingredient, it can lead to irritation or dryness," says Dr. Garshick. "In some cases, prolonged use of antibiotics can trigger a different type of breakout known as pityrosporum folliculitis which should be evaluated by a dermatologist." If you notice that your skin is getting significantly worse, contact your doctor so they can assess what steps to take next.

"There's no real skin type or group of people that would have to avoid using clindamycin," Dr. Karam adds. "It's a pretty safe, broad class of antibiotics that can be used as a primary treatment for acne. It is also often combined with Retin-A as well as benzoyl peroxide. The three of those typically become a standard first-line treatment for most acne cases."

Oh, and yes, clindamycin does make your skin more sensitive to the sun, so be sure to stock up on the sunscreens and apply them daily.

How to Use It

Clindamycin can be used once or twice daily during your AM and PM routine. According to Dr. Garshick, it's typically prescribed in a topical form that can be a gel, lotion, solution, foam, or wipe, depending on your skin type and what area you need it for. Wipes are great for large areas like the back and chest, while gels work great for people with oily skin types. Your dermatologist may also prescribe topical clindamycin in combination with fellow acne-fighting ingredients like adapalene or benzoyl peroxide for greater efficacy.

"Importantly, to minimize the chance of antibiotic resistance, it is best to use in conjunction with benzoyl peroxide which works to reduce the potential for antibiotic resistance," says Dr. Garshick. "The location being treated can guide the optimal formulation to use, with the solution being helpful in hair-bearing areas and the gel being good for oily areas."

You'll need to use it for about three months to potentially see results, adds Dr. Karam.